Bassem Mohamed Elsawy
Assistant Professor of Physiology
Bassem Mohamed Alsawy
Current work: (Assistant professor of Physiology)
Faculty of Medicine Male Campus
Tabuk University (KSA)
In Egypt: (Lecturer of Physiology- Faculty of Medicine- Bani Swaf University a branch of Faculty of Medicine- Cairo University)
In KSA: (00966503597630)
In Egypt (00201118078562)
Arab Republic of Egypt.
Military Status: Completed
M.D. Dept. of Physiology, Faculty of Medicine, Cairo University, October, 2008.
M.S. Dept. of Physiology, Faculty of Medicine, Cairo University, July 2002.
M.B.B.ch. Faculty of Medicine, Cairo University, December 1994.
Professional Experience (academia)
- House Officer, Cairo University Hospitals From 1995 Till 1996.
- Resident in Internal Medicine Department, Cairo University Hospital From 1997 till 1998.
- Resident of Physiology, Department of Physiology, Faculty of Medicine, Cairo University From 1999 till 2002.
- Assist Lecturer of Physiology, Department of Physiology, Faculty of Medicine, Cairo University (Beni Swaif Branch) From 2002 till 2008.
- Lecturer of Physiology, Department of Physiology, Faculty of Medicine, Cairo university (Beni Swaif Branch), From 2008 till now.
-Present Work: Assistant professor of Physiology , Faculty of medicine, Tabuk University.
Member of Quality and Accreditation Committee, Faculty of Medicine, University of Tabuk.
Member of Strategic Plan Committee, Faculty of Medicine, University of Tabuk.
Member of PBL Committee, Faculty of Medicine, University of Tabuk.
Summary Of Teaching Experiences:
In this position I am teaching the following Physiology courses:
Body compartments and body fluid
The cell membrane: structure and function
Transport through the cell membrane:
Diffusion & osmosis, active transport and vesicular transport
Intercellular communication & control systems
This course covers the basic knowledge of the normal functioning of the body with particular reference to basic body homeostasis.
This course aims to provide an understanding of essential concepts in physiology:
Cell structure and function:
Nucleus & nucleoses, mitochondria, lysosomes, golgi apparatus, centrioles, endoplasmic reticulum (rough & smooth) and cytoskeleton of the cell.
This course will introduce students to selected topics in current research in cell biology. There will be an emphasis upon looking at the dynamics of living cells. Topics covered will include phospholipid and calcium signaling, gene regulation, endocytosis and exocytosis, the cell cycle, mitochondria and apoptosis, proteolysis, cell senescence, and the role of cytoskeleton in cell motility.
Composition and function of blood
Red blood cells (haemoglobin, erythropoiesis and some physical properties of the blood) and anaemia
White blood cells (types of leucocytes & the inflammatory response) and immunity
Blood platelets , hemostasis, abnormalities and anticlotting mechanisms
The course begins by considering the physiology of essential components of the blood, blood functions and all defensive mechanisms of the body against any invading organisms
Mention the general components of blood and its functions, mechanism of blood coagulation and regulation of blood volume and understand some of clinical conditions occurring due to deficiency of one or more of the blood components.
Autonomic nervous system
Functions of sympathetic N.S.
Functions of parasympathetic N.S.
Autonomic receptors and transmission
Adrenal medulla & drugs that affect the A.N.S
For students to obtain an increase in their knowledge of autonomic physiology (involuntary functions of the body).
Describe the structure and functions of the Autonomic nervous system, its higher centers, autonomic receptors and chemical transmitters
Nerve & Muscle
Resting membrane potential
Measuring & calculation of R.M.P and all or non law
Excitation and conduction
Nerve action potential .
Skeletal muscle contraction and its properties .
Plain muscles , electrical & mechanical properties .
The course begins by considering the anatomy and physiology of essential components of the motor system; muscles and the motor unit
-The existence of resting membrane potential
Mention the properties of excitability of living tissues , membrane potentials , and their relation to different phases of excitability , physiological anatomy of the skeletal muscle and mechanism of contraction and changes occurring during it.
Cardiac muscle properties
Electrical properties of c. muscle: sinus rhythm , action potential .
ECG : methods of recording ,normal record and
common abnormalities .
_ Mechanical properties of c. muscle .
_ Cardiac cycle .(heart sounds)
_ Cardiac output , and factors affecting .
_ Work of heart , mechanical efficiency , cardiac
reserve & metabolism of c. muscle.
_ Hemodynamics .
_ Arterial blood pressure , factors controlling it and its
_ Capillary & lymphatic circulation
_ Special circulation : coronary , pulmonary and
_ Hemorrhage shock and muscle exercise .
The course builds upon your primary knowledge of the heart and circulation. Essential aspects of cardiac and vascular physiology will be considered. This will enable you to grasp a number of areas of experimental, applied and patho- physiology.
Functional anatomy .
_ Pulmonary ventilation , compliance , work of
breathing and V/P ratio .
_ Pulmonary function tests .
_ Exchange of gases through the pulmonary
membrane and gas transport .
_ Regulation of respiration .
_ Hypoxia , cyanosis , and dyspnea .
_ Effect of hyperbaric oxygen & deep sea diving .
The course begins with a review of some basic concepts relevant to the understanding of respiratory physiology. We will then build on these basic concepts to introduce and explain how breathing is monitored and controlled in a range of physiological and pathophysiological situations. Although the emphasis is on respiration in health and disease in humans, we will draw on evidence obtained in animal experimentation to illustrate the underlying mechanisms involved in ventilatory control. Throughout, there will be emphasis on the methodology used in particular studies and their limitations.
Salivary secretion , mastication and deglutition
Gastric secretion, motility , gastric evacuation and vomiting
Hepatic secretion , gall bladder and jaundice
Small & large intestine
Gastrointestinal motility and GIT hormones
This is responsible for changing the food into substances that can be recognized and used by the cells of the body.
Explain the general mechanism of the gastrointestinal secretion, components of functions of different parts of the digestive system the mechanism of absorption, types of gastrointestinal movements and some clinical conditions, which result from disturbances of functions.
The central nervous system
General functional organization
Somatic sensations .
Synapses of the CNS, & chemical transmitters .
Organisation of the motor control : spinal , descending motor
system , cortical motor areas .
Spinal cord reflexes , stretch reflex , upper and low er motor
neurone lesions .
Basal ganglia & cerebellum : functions and sysdromes .
Vestibular apparatus & control of posture .
Hypothalamus & limbic system .
RAS , consciousness and sleep .
The neurophysiological basis of learning & memory .
The aim of the course is to provide an introduction to the production transmission and integration of signals within the nervous system. The biophysics of neural membranes is considered along with the physiology and pharmacology of synaptic transmission. This cellular introduction to the nervous system is followed by consideration of sensory systems, motor control and higher nervous activity in man. Problems in developmental neurobiology and neurogenetics will also be discussed.
The course covers the following levels of description of brain function. These include:
This course aims to present an integrated approach to pain.
Functional structure of the eye , lachrymal apparatus and
protection of the eye .
Refractive power of the eye , functions of iris , aqueous humour ,
and retina .
Visual acuity , colour and binocular vision .
Visual pathway and role of cortical areas in perception of vision .
Functional structure of the external , middle and internal ears .
Mechanism of sound transduction , auditory pathway and auditory perception .
Deafness and testing for deafness .
Smell & taste , receptors and pathway .
It presents the neurobiology of vision, hearing, taste and smell from a multidisciplinary point of view that includes anatomical, physiological, genetic and psychological perspectives. This integrated approach provides insights into special senses function and processing not only from the level of the single cell but also from the level of the organism as a whole.
Pituitary gland : anterior & posterior
Parathyroid gland , Vitamin D3 and calcitonin .
Suprarenal cortex : glucocorticoids , mineralocorticoids and adrenal androgens
Endocrine pancreas : insulin and glucagon
This is the glandular system. It uses chemical messengers called hormones to carry instructions around the body. The health of the body depends on a correct hormonal balance.
Functional structure of the kidney
Tubular segments function
Renal Function tests
This gets rid of the waste fluid from the blood and is responsible for maintaining the liquid balance of the body.
Male reproduction : functional structure , spermatogenesis , blood
testis barrier , male sex hormones control & actions .
Female reproduction : functional structure , female sex cycles ,
ovulation , female sex hormones control & actions .
Physiology of pregnancy and lactation .
Physiology of puberty .
Reproduction System Responsible for continuation of the species.
Metabolism & regulation of body
Energy balance and metabolic rate .
Basal metabolic rate
Body temperature , control of body temperature
All chemical changes occurring inside the body
Physiology safety information
Light Microscope: parts and how to use
Estimation of Hemoglobin content
Determination of Hematocrit value
Estimation of ESR
Detection of Blood Grouping
Measuring of ABP
Measuring of Arterial Pulsation
Best sites of hearing
How to do.
Types of Apnea
Measurements of Lung volumes and Capacities
Examination of nervous system (Clinical examination)
Examination of Somatic sensations:
Touch, Pressure sense, Worm & Cold senses, Pain sense, Vibration sense, Stereognosis and Itching & Tickling
Deep reflexes (Tendon Jerk)
Examination of muscle tone
Corneal reflex, Light reflex and Near response
Measuring of Visual Acuity (Snellen's Chart)
Tests for Color Blindness (Ishihara Chart Test)
Tests for Detection types of Deafness:
Rinne and Weber tests
Mapping the tongue for different tastes
Detecting the pH and Specific gravity of urine (Urinometer)
Measuring of body temperature and detection of body mass index
Undergraduate Research Assistants
1- Mashari Albalawi, Liver Macrophages, 2008.
2- Mansour Mosallam, Aids, 2008.
3- Nayef Faraj, Bronchial asthma, 2008.
4- Mohamed Almansoury, white blood cells, 2008.
5- Majed Ahmed, Lieshmaniasis, 2009.
6- Mohanned Jabr, Osteoclastes, 2009.
7- Nawaf Saud, Microtomes, 2009.
8- Walied Soliman, Osteaporosis.
9- Hamed Alanazi, Diabetes Insipidus, 2009.
10- Osman Alshredi, Insulin Resistance, 2009.
11- Mashari Mostafa Al Ali, Role of Adeponectin in Ameliorating Insulin resistance, 2010.
Funding (Not including Consulting)
1- University of Cairo, Distance Learning Program Equipment Grant, March 20, 2002, $250.0
2- University of Cairo, Institute for Heart Diseases and Hypertention Fellowship for Fifth Annual Meeting of Young Investigators 2003, $250.0+ conference expenses.
Publications in Refereed Journals
- Adverse Effects of Organophosphorus Insecticides On Macrophage Activity In Persons at High Risk For Parasitic Infection (Macedonian Journal of Medical Sciences)
Magdi N. Ashour1 ; Baseem M. Elsawy2 and Mohamed Eissa Mohamed3 (2011):
- Nasal Spirometry: A New Approach for Spirometry to Evaluate Respiratory Functions
Nasr A. Belacy, MD1,2,*, Tawfik M. Ghabrah, MD3, Moustafa H. Abdelsalam, MD1,4, Magdi A. El-Damarawi, MD1,5, Basem M. Elsawy, MD1,6, Noha A. Nasif, MD1,7, Eman A. El-Bassuoni, MD1,8
Basic Sciences of Medicine 2014, 3(2): 30-35 DOI: 10.5923/j.medicine.20140302.03
- Reference Values for Lung Function Tests in Adult Saudi Population
Nasr A. Belacy1,2, Abdullah H. Altemani3, Mostafa H. Abdelsalam1,4,*, Magdi A. El-Damarawi1,5, Basem M. Elsawy1,6, Noha A. Nasif1,7, Eman A. El-Bassuoni1,8
- Effect of Diabetes Mellitus and Its Control on Myocardial Contractile Function in Rats
Bassem M. Alsawy1,3, Magdi A. El-Damarawi2,3*
Macedonian Journal of Medical Sciences.
- Effect of Diet Restriction and Exercise on Plasma Adiponectin Level and Adiponectin Receptor Expression in Obese Diabetic Rats
Magdi A. El-Damarawi 1,3, Bassem M. Alsawy 2,3
Papers Submitted for Review
- Effect of High Intensity Interval Training on Different Parameters of ECG on Normal Subjects
Conference and Workshop Presentations
1- Effect of pH and the sudden temperature changes on the contraction of skeletal muscle (diaphragm). The Third Scientific Meeting Of Clinical Physiology Department, Update In Microbiology And Immunology, Cairo, Egypt, 16 February 2006.
2 -The Effect of Garlic and Onion on diabetic patients (levels of blood glucose and the complications). The Thirteenth Annual Conference Of The Faculty Of Medicine, Cairo University, Egypt, 21-24 November 2006.
3- Fourth International Conference of the Egyptian Society of Pediatric Hematology Oncology. Cairo, Egypt, 30-31 March 2006.
4 - Effect of Melatonin and Endothelin blocker on Ischemia Reperfusion condition of the Isolated rat heart. The First Scientific Meeting Of Clinical Physiology Department In Collaboration with Internal Medicine Department, Cairo, Egypt, 19 April 2005.
5- Interaction between Leptin release and Body weight in Smoking Obese patients. The Sixteenth Annual Conference Of The Egyptian Society Of Laboratory Medicine In Collaboration With The Egyptian Society Of Applied Endocrinology, Obesity: Global Health problem, Cairo, Egypt, 23-24 March, 2005.
6- The Second Scientific Meeting of Clinical Physiology Department, Automation in Hematology, Cairo, Egypt, 27 September 2005.
7- The Seventh Annual Conference Of Clinical Pathology And The Fourth Egyptian-French Seminar Of Immunology And Molecular Biology, Mansoura, Egypt, 19-20 March 2005.
- A member of Egyptian Society of Physiology.
- A member of evolve Elsevier of textbook of physiology.
1- Egyptian Journal of Physiology.
2- Macedonian Journal of Medical Sciences.
Workshops and Institutes Attended in Saudi Arabia:
1- Workshop on Use of Communication and Information Technology in Academic Teaching, university of tabuk, 16/4/2009.
2- Symposium on (Pharmaceutical care : Notion and Implementation)
Accredited by the Saudi council for health specialies, 7 – 8/4/2009.
3- Participant in the workshop on strategy preparation of Tabuk university,
4 – 5 – 6 /5/2009.
4- Work shop on Application of Quality Control in Academic Performance, Tabuk university, 23 – 24/11/1430.-
5- Workshop on Principles and awareness of quality control and certificate accreditation, Tauk university, 12/2/1429.
6- Work shop on planning a teaching session, Monash University (Tabuk), December 2010.
7- Work shop on teaching for interactive learning, Monash University (Tabuk), December 2010.
8- Work shop on teaching small groups, Monash University (Tabuk), December 2010.
9- Work shop on dealing with the poorly performing learner, Monash University (Tabuk), December 2010.
10. Workshop on application of power Lab in education, AD instruments (Tabuk University) 2011.
11. Workshop on writing smart learning objectives, (Faculty of Medecine, Tabuk University) 2011.
12- Work shop on way of performing strategic plan for faculty of medicine, National organization for Assessment and Accreditation, 2012.
13- Work shop on quality control and programs evaluation: Tabuk University and National organization for Assessment and Accreditation 2013.
14- Recent Advance in the Management of Type 1 and Type 2 Diabetes: A USA (International) and KSA (National) Preservative, 2013.
15- Work shop on performing, reporting and fulfilling program specification: Tabuk University and National organization for Assessment and Accreditation 2013.
16- Work shop on performing and reporting course specification: Tabuk University and National organization for Assessment and Accreditation 2013.
17- MD consult and clinical key training session held at university of Tabuk 2013.
18- Work shop on participation as an examiner in the Triple Jump Exam (TJE): Tabuk University 2013.
19- Work shop on key Performance Indecators (KPIs) and Benchmarking: Tabuk University and National organization for Assessment and Accreditation 2013.
20- Work shop on Key performance Indicators for Program Self Assessment : Tabuk University and National organization for Assessment and Accreditation 2014.
21- Work shop on Key performance Indicators for Program: Tabuk University and National organization for Assessment and Accreditation 2014.
22- Work shop on Smart board: Quality and Improvement committee, Tabuk University 2/11/2014.
23- Work shop on ECG Basics and Interpretation : Department of Physiology, Faculty of Medicine, Tabuk University 1/2/2015.
24- Work shop on Measurements and Evaluation at Universities Between Theory and Practice: Tabuk University in collaboration with the National Center for Assessment in Gigher Education 2 - 3/3/2015.
Adverse Effects of Organophosphorus Insecticides on
Background: It has been suggested that acute exposure to pesticides altered the ability of macrophages
to overcome the pathogen invasion.
Aim: To evaluate the levels of NO, IFN-? and arginase in both rats and CL patients exposed daily to the
CPF pesticide. Also, to evaluate the benefits of curcumin and/or arginine as a prophylactic agents.
Materials and Methods: Plasma samples from 25 CL patients, 10 healthy control and CPF-treated rats,
divided into five groups, were extracted. Also, PBMNCs recruited only from CL patients.
Results: A significant increase in the level of arginase coupled with a significant decrease in the levels
of NO and INF-? were observed in CPF-treated animals. Restoration of the previous biochemical
markers were significantly observed when a mixture of curcumin and arginine was used as a
prophylactic remedy. In CL patients, a significant increase in the level of arginase activity was noticed.
However, when curcumin is added to the cultural media containing active PBMNCs recruited from CL
patients, a significant decrease in the level of NO associated with an increase in the arginase levels were
Conclusion: The negative effect of CPF on macrophage activity can be attenuated by oral intake a
mixture of curcumin and arginine.
Face mask vs mouth piece spirometry in Healthy Adults
INTRODUCTION AND AIM:
Spirometry is a commonly used test for respiratory function parameters (1-3) Prediction values are affected by sex, age, height, weight and also by ethnic groups (1,4). No reference values for people in Saudia Arabia, especially in adult age is available until now.
Only conventional Spirometry using the mouth tube is used (1,4,7). This method is not suitable for many users including young children and elder people as well as many of the neurological patients due to air leakage around the mouth piece. Trials with different mouthpieces (3), two mouth pieces (6) and even by holding the lips (2) were recorded. Recently a face mask spirometry was tried as an alternative method for neurological patients (5).
Aim of the work:
This work aims at:
1- Determines the reference values of some of the static and dynamic pulmonary function tests in adult age in Saudi Arabia.
2- Test for the validity of using face mask mouth spirometry for both static and dynamic pulmonary function tests as an alternative method to traditional mouth piece spirometry.
3- Test for the value of using the nasal route instead of the mouth route for measuring the pulmonary function parameters using the face mask spirometry.
Subjects and methods
Subjects: 500 healthy male adults never smoked students will be randomly chosen from different colleges of Tabuk university. Students of each college will be visited and they will be explained about the tests and procedures. They will be tested for pulmonary functions using mouth piece and face mask spirometry. For every student the data of sex, age, height and weight will be determined and reported.
Spirometry: The following parameters will be tested: TV,VC, FVC, FEV1 and PEF using Spirolab II spirometer with the alternative use of mouth piece connection and face mask connection (via mouth route and nasal route).
The data collected will be entered in the SPSS software and analyzed statistically.
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