The Department of Pathology is one of the foundation departments within the Faculty of Medicine of Tabuk University. On an academic level, the study of pathology is elementary for clinical practice, and a good quality clinician must have good knowledge of pathology. The Department of Pathology is responsible for the teaching of Pathology to Medical students and Applied Medical Science students and in the near future for Dental students. For undergraduate studies, the department begins to receive the second-year medical students in the academic year 1429-1430 (2008-2009) for the male section and in 1430-1431 (2009-2010) for the female section. What is Pathology? Pathology is the study of diseases; dealing with their etiology, mechanism (pathogenesis), morphological features (gross and microscopic), fate, effects and prognosis. It is a discipline which investigates human disease at every level from the molecule to the population. The aims of these investigations is to understand disease processes, then help to develop management and treatment strategies, or even better, prevent disease from occurring. For a student of medicine, pathology is thus the bridge between the basic sciences taught largely in the preclinical part of most curricula and the practice of clinical medicine. Studying Pathology at the University of Tabuk Pathology is traditionally learnt in two stages: general pathology and systemic pathology. The former focuses on the fundamental cellular and tissue responses to pathologic stimuli, while the latter studies the specific diseases that affect individual organs or systems. The principles of general pathology must be understood before an attempt is made to study systemic pathology. In the curriculum of Tabuk Faculty of Medicine, pathology is, currently, taught with other subjects in an integrated course. So, general pathology is included with other subjects in the abnormal human morphology module given in the second semester of the second year for medical students. Systemic pathology is covered in different body system modules given in the second and third year of the faculty. The main features of the module are the integration of knowledge and a taste of clinical aspects. The study guide will show the necessary items related to each subject.